AQ4

• 产品号: A9236
• CAS号: 70476-63-0
• 分子式: C22H28N4O4
• 分子量: 412.48212
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: AQ4
• IUPAC标准名: 1,4-bis({[2-(dimethylamino)ethyl]amino})-5,8-dihydroxy-9,10-dihydroanthracene-9,10-dione
• IUPAC传统名: 1,4-bis({[2-(dimethylamino)ethyl]amino})-5,8-dihydroxyanthracene-9,10-dione
• 别名: 1,4-Bis[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione; 1,4-Bis[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxyanthracene-9,10-dione

产品登记号

• CAS号: 70476-63-0
• MDL号: MFCD02656425

产品性质

• Empirical Formula (Hill Notation): C22H28N4O4
• 纯度: ≥98% (HPLC)
• 外观: dark blue powder
• 溶解度: DMSO: ≥10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H410
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273-P501
• RID/ADR: UN 3077 9/PG 3
• 危险公开号: 22-50/53
• 安全公开号: 22-60-61
• 保存条件: desiccated
• 保存温度: 2-8°C
• 联合国危险货物等级: 9
• 联合国危险货物编号: 3077
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
AQ4 is a chemically stable cytotoxic agent which acts as a topoisomerase II inhibitor and DNA intercalator. The compound is a potent cytotoxic agent in many human tumor lines, including those derived from human pancreatic adenocarcinomas. The compound N-oxide is a hypoxia activated prodrug of topoisomerase-targeting.

详细说明 (简体中文)

Biochem/physiol Actions
AQ4 is a chemically stable cytotoxic agent which acts as a topoisomerase II inhibitor and DNA intercalator. The compound is a potent cytotoxic agent in many human tumor lines, including those derived from human pancreatic adenocarcinomas. The compound N-oxide is a hypoxia activated prodrug of topoisomerase-targeting.