Cardamonin

• 产品号: C8249
• CAS号: 19309-14-9
• 分子式: C16H14O4
• 分子量: 270.27996
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Cardamonin
• IUPAC标准名: 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
• IUPAC传统名: cardamomin
• 别名: (E)-2′,4′-Dihydroxy-6′-methoxy-chalcone; (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one; (8CI); Alpinetin chalcone

产品登记号

• MDL号: MFCD00238554
• CAS号: 19309-14-9

产品性质

• Empirical Formula (Hill Notation): C16 H14 O4
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: DMSO: ≥20 mg/mL
• GHS警示词: Warning
• GHS危险声明: H400
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273
• RID/ADR: UN 3077 9/PG 3
• 危险公开号: 50/53
• 安全公开号: 61
• 保存温度: room temp
• 联合国危险货物等级: 9
• 联合国危险货物编号: 3077
• 联合国危险货物包装类别(PG): 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Cardamonin is a calchone from Aplinia species (zingiberaceous plant species). Cardamonin inhibits pigmentation in melanocytes through suppression of Wnt/b-catenin signaling pathway. Cardamonin suppressed Wnt/b-catenin signaling by a mechanism involving proteasome-mediated degradation of b-catenin (GSK-3b-independent pathway). Research has shown that Cardamonin possesses anti-inflammatory activity via suppression of NF-kB nuclear translocation and Ik-Ba phosphorylation.

详细说明 (简体中文)

Biochem/physiol Actions
Cardamonin is a calchone from Aplinia species (zingiberaceous plant species). Cardamonin inhibits pigmentation in melanocytes through suppression of Wnt/b-catenin signaling pathway. Cardamonin suppressed Wnt/b-catenin signaling by a mechanism involving proteasome-mediated degradation of b-catenin (GSK-3b-independent pathway). Research has shown that Cardamonin possesses anti-inflammatory activity via suppression of NF-kB nuclear translocation and Ik-Ba phosphorylation.