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Dehydroleucodine

产品号 D4196 公司名称 Sigma Aldrich
CAS号 36150-07-9 公司网站 http://www.sigmaaldrich.com
分子式 C15H16O3 电 话 1-800-521-8956
分子量 244.28574 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 desiccated Chembase数据库ID: 154820

产品价格信息

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产品别名

标题
Dehydroleucodine
IUPAC标准名
(3aS,9aS,9bS)-6,9-dimethyl-3-methylidene-2H,3H,3aH,4H,5H,7H,9aH,9bH-azuleno[4,5-b]furan-2,7-dione
IUPAC传统名
(3aS,9aS,9bS)-6,9-dimethyl-3-methylidene-3aH,4H,5H,9aH,9bH-azuleno[4,5-b]furan-2,7-dione
别名
dehydro-
Lidbeckialactone
Dehydroleucodin
11,13-Dehydroleucodin
Leucodin
Mesatlantin E
NSC 180034
[3aS-(3aalpha,9aalpha,9bbeta)]-3,3a,4,5,9a,9b-hexahydro-6,9-dimethyl-3-methylene-azuleno[4,5-b]furan-2,7-dione

产品登记号

MDL号 MFCD06794926
CAS号 36150-07-9

产品性质

Empirical Formula (Hill Notation) C15H16O3
纯度 ≥98% (HPLC)
外观 white to off-white powder
溶解度 DMSO: ≥30 mg/mL
MSDS下载 下载链接
保存条件 desiccated
保存条件 protect from light
保存条件 under inert gas
保存温度 room temp
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. An extract from the plant is widely used in Cuyo region (Argentina) as folk medicine for the treatment of gastric ailments. The compound prevents gastric and duodenal damages in response to necrosis-inducing agents. Stabilization of mast cells may be a key mechanism to protect the gastrointestinal tract from injury and ulceration. Recently, it was established that dehydroleucodine and xanthatin inhibit mast cell degranulation induced by compound 48/80.
详细说明 (简体中文)
Biochem/physiol Actions
Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser; mast cell stabilizers. An extract from the plant is widely used in Cuyo region (Argentina) as folk medicine for the treatment of gastric ailments. The compound prevents gastric and duodenal damages in response to necrosis-inducing agents. Stabilization of mast cells may be a key mechanism to protect the gastrointestinal tract from injury and ulceration. Recently, it was established that dehydroleucodine and xanthatin inhibit mast cell degranulation induced by compound 48/80.

参考文献