Asenapine maleate

• 产品号: A7861
• CAS号: 85650-56-2
• 分子式: C21H20ClNO5
• 分子量: 401.8402
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Asenapine maleate
• IUPAC标准名: (2S,6S)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.0^2,^6.0^7,^1^2]octadeca-1(18),7,9,11,14,16-hexaene; but-2-enedioic acid
• IUPAC传统名: asenapine; butenedioic acid
• 别名: trans-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate; (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12btetrahydro-1Hdibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-butenedioate; Org 5222

产品登记号

• EC号: 288-064-8
• CAS号: 85650-56-2

产品性质

• Empirical Formula (Hill Notation): C17H16ClNO ·C4H4O4
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: H2O: ≥10 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301-H315-H319-H335-H400
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P261-P273-P301 + P310-P305 + P351 + P338
• 危险公开号: 22-36/37/38-50/53
• 安全公开号: 26-60-61
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Asenapine maleate is a 5-HT receptor antagonist (5-HT1A,1B, 5-HT2A, 2B, 2C, 5-HT5A, 5-HT6 and 5-HT7), a D2 antagonist, and an antipsychotic.
Application
Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania.

详细说明 (简体中文)

Biochem/physiol Actions
Asenapine maleate is a 5-HT receptor antagonist (5-HT1A,1B, 5-HT2A, 2B, 2C, 5-HT5A, 5-HT6 and 5-HT7), a D2 antagonist, and an antipsychotic.
Application
Asenapine maleate is a serotonin 5-HT and dopamine D2 receptor antagonist. Asenapine maleate can be used to treat schizophrenia and bipolar mania.