Rifapentine

• 产品号: R0533
• CAS号: 61379-65-5
• 分子式: C47H64N4O12
• 分子量: 877.03066
• 纯 度: ≥93%

产品别名

• 标题: Rifapentine
• IUPAC标准名: (7S,12R,13S,14R,15R,16R,17S,18S)-26-[N-(4-cyclopentylpiperazin-1-yl)carboximidoyl]-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13-yl acetate
• IUPAC传统名: (7S,12R,13S,14R,15R,16R,17S,18S)-26-[N-(4-cyclopentylpiperazin-1-yl)carboximidoyl]-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^4,^7.0^5,^2^8]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13-yl acetate
• 别名: DL 473

产品登记号

• CAS号: 61379-65-5
• EC号: 262-743-9

产品性质

• Empirical Formula (Hill Notation): C47H64N4O2
• 纯度: ≥93%
• 运输包装: wet ice
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• RTECS编号: JQ0902000
• 安全公开号: 26
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Rifapentine is an antibiotic clinically used to treat tuberculosis. It is used in tuberculosis research1.
Biochem/physiol Actions
Semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacterial and against Mycobacterium tuberculosis.2 Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription.3
Rifapentine is a semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacteria and against Mycobacterium tuberculosis. Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription. It interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme1.

详细说明 (简体中文)

Application
Rifapentine is an antibiotic clinically used to treat tuberculosis. It is used in tuberculosis research1.
Biochem/physiol Actions
Semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacterial and against Mycobacterium tuberculosis.2 Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription.3
Rifapentine is a semisynthetic derivative of rifampicin with antibacterial activity against Gram-positive and Gram-negative bacteria and against Mycobacterium tuberculosis. Rifapentine inhibits DNA-dependant RNA polymerase and prevents RNA transcription. It interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme1.