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Azide cyanine dye 728_分子结构_CAS_1188332-22-0)
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Azide cyanine dye 728

产品号 89524 公司名称 Sigma Aldrich
CAS号 1188332-22-0 公司网站 http://www.sigmaaldrich.com
分子式 C40H52N6O6S2 电 话 1-800-521-8956
分子量 777.00748 传 真
纯 度 电子邮件
保 存 Chembase数据库ID: 154781

产品价格信息

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产品别名

标题
Azide cyanine dye 728
IUPAC标准名
2-(2-{2-[(3-azidopropyl)amino]-3-{2-[3,3-dimethyl-1-(4-sulfobutyl)-2,3-dihydro-1H-indol-2-ylidene]ethylidene}cyclopent-1-en-1-yl}ethenyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium
IUPAC传统名
2-(2-{2-[(3-azidopropyl)amino]-3-{2-[3,3-dimethyl-1-(4-sulfobutyl)indol-2-ylidene]ethylidene}cyclopent-1-en-1-yl}ethenyl)-3,3-dimethyl-1-(4-sulfonatobutyl)indol-1-ium
别名
2-{2-{2-[(3-Azidopropyl)amino]-3-{2-[1,3-dihydro-3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene}-1-cyclopenten-1-yl}ethenyl}-3,3-dimethyl-1-(4-sulfobutyl)-3H-indolium inner salt

产品登记号

CAS号 1188332-22-0
MDL号 MFCD18452836

产品性质

Empirical Formula (Hill Notation) C40H52N6O6S2
荧光 λex 670 nm; λem 728 nm in ethanol
GHS危险品标识 GHS07
GHS警示词 Warning
GHS危险声明 H315-H319-H335
欧盟危险性物质标志 刺激性(Irritant) 刺激性(Irritant) (Xi)
MSDS下载 下载链接
GHS警示性声明 P261-P305 + P351 + P338
危险公开号 36/37/38
安全公开号 26
保存温度 -20°C
德国WGK号 3

产品详细信息

详细说明 (English)
General description
The MegaStokes dyes for ?click" biological labeling, licensed by LuminoChem are virtually covering the whole visible spectrum reaching the infra-red regime. Besides dyes that are being capable of participating in classical copper catalyzed 1,3-dipolar cycloaddition reaction with the counterparting function, we also provide dyes containing cyclooctyne moiety an alkyne derivative that enables copper free clicking to azides.These dyes are noteworthy for their large Stokes-shift (120 or 125 nm). Dyes for this kind are exceptionally useful in fluorescence resonance electron transfer (FRET) applications as they do not interfere with the spectral bands of the second fluorophore a common problem in FRET technology. Azido sugars have been used for click-labeling of surface glycoproteins, recently. We have adapted this system to demonstrate the ability of our dyes to undergo bioorthogonal labeling reaction, efficiently. Prior to labeling, Chinese hamster ovary (CHO) cells were incubated with these MegaStockesdyes to test the possible cytostatic effects of these dyes. Experimental results have shown that neither dye is toxic up to 50 μM concentration.
详细说明 (简体中文)
General description
The MegaStokes dyes for ?click" biological labeling, licensed by LuminoChem are virtually covering the whole visible spectrum reaching the infra-red regime. Besides dyes that are being capable of participating in classical copper catalyzed 1,3-dipolar cycloaddition reaction with the counterparting function, we also provide dyes containing cyclooctyne moiety an alkyne derivative that enables copper free clicking to azides.These dyes are noteworthy for their large Stokes-shift (120 or 125 nm). Dyes for this kind are exceptionally useful in fluorescence resonance electron transfer (FRET) applications as they do not interfere with the spectral bands of the second fluorophore a common problem in FRET technology. Azido sugars have been used for click-labeling of surface glycoproteins, recently. We have adapted this system to demonstrate the ability of our dyes to undergo bioorthogonal labeling reaction, efficiently. Prior to labeling, Chinese hamster ovary (CHO) cells were incubated with these MegaStockesdyes to test the possible cytostatic effects of these dyes. Experimental results have shown that neither dye is toxic up to 50 μM concentration.

参考文献