3′,4′-Dimethoxyflavone

• 产品号: D6571
• CAS号: 4143-62-8
• 分子式: C17H14O4
• 分子量: 282.29066
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: 3′,4′-Dimethoxyflavone
• IUPAC标准名: 2-(3,4-dimethoxyphenyl)-4H-chromen-4-one
• IUPAC传统名: 2-(3,4-dimethoxyphenyl)chromen-4-one
• 别名: 2-(3,4-Dimethoxyphenyl)chromen-4-one; 3′,4′-DMF

产品登记号

• MDL号: MFCD00143009
• CAS号: 4143-62-8

产品性质

• Empirical Formula (Hill Notation): C17H14O4
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: DMSO: ≥20 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• GHS警示性声明: P301 + P310
• 危险公开号: 25
• 安全公开号: 45
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
3′,4′-dimethoxyflavone is a competitive antagonist of the AhR that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines. The compound blocks transformation of the cytosolic AhR complex, and formation of nuclear AhR complexes.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D6571.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

详细说明 (简体中文)

Biochem/physiol Actions
3′,4′-dimethoxyflavone is a competitive antagonist of the AhR that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines. The compound blocks transformation of the cytosolic AhR complex, and formation of nuclear AhR complexes.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D6571.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.