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Frondoside A hydrate

产品号 F0808 公司名称 Sigma Aldrich
CAS号 127367-76-4(anhydrous) 公司网站 http://www.sigmaaldrich.com
分子式 C60H95NaO29S 电 话 1-800-521-8956
分子量 1335.43367 传 真
纯 度 ≥96% (HPLC) 电子邮件
保 存 desiccated Chembase数据库ID: 154767

产品价格信息

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产品别名

标题
Frondoside A hydrate
IUPAC标准名
sodium 6-{[(2S,4S,5R,6S,13R,16S,18R)-4-(acetyloxy)-2,6,13,17,17-pentamethyl-6-(4-methylpentyl)-8-oxo-7-oxapentacyclo[10.8.0.02,9.05,9.013,18]icos-1(20)-en-16-yl]oxy}-5-({5-[(4-{[3,5-dihydroxy-6-(hydroxymethyl)-4-methoxyoxan-2-yl]oxy}-3,5-dihydroxyoxan-2-yl)oxy]-4-hydroxy-6-methyl-3-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl}oxy)-4-hydroxyoxan-3-yl sulfate
IUPAC传统名
sodium 6-{[(2S,4S,5R,6S,13R,16S,18R)-4-(acetyloxy)-2,6,13,17,17-pentamethyl-6-(4-methylpentyl)-8-oxo-7-oxapentacyclo[10.8.0.02,9.05,9.013,18]icos-1(20)-en-16-yl]oxy}-5-({5-[(4-{[3,5-dihydroxy-6-(hydroxymethyl)-4-methoxyoxan-2-yl]oxy}-3,5-dihydroxyoxan-2-yl)oxy]-4-hydroxy-6-methyl-3-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl}oxy)-4-hydroxyoxan-3-yl sulfate

产品登记号

CAS号 127367-76-4(anhydrous)

产品性质

Empirical Formula (Hill Notation) C60H95O29S·Na · xH2O
纯度 ≥96% (HPLC)
外观 white to off-white powder
溶解度 H2O: ≥10 mg/mL
MSDS下载 下载链接
保存条件 desiccated
保存温度 -20°C
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Frondoside A is a bioactive triterpenoid saponin from sea cucumber; and an immunostimulant. Frondoside A is an extremely potent inducer of apoptosis, and although it does activate caspaces, it can induce apoptosis in HL-60 cells through a mechanism distinct from extrinsic and intrinsic apoptosis pathways. It potentially valuable for cancers that are resistent to other apoptosis inducers, such as pancreatic cancer.
详细说明 (简体中文)
Biochem/physiol Actions
Frondoside A is a bioactive triterpenoid saponin from sea cucumber; and an immunostimulant. Frondoside A is an extremely potent inducer of apoptosis, and although it does activate caspaces, it can induce apoptosis in HL-60 cells through a mechanism distinct from extrinsic and intrinsic apoptosis pathways. It potentially valuable for cancers that are resistent to other apoptosis inducers, such as pancreatic cancer.

参考文献