n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate

• 产品号: A0987
• 分子式: C22H34O5
• 分子量: 378.50236
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate
• IUPAC标准名: pentyl 2-(3,5-dihydroxy-2-nonanoylphenyl)acetate
• IUPAC传统名: pentyl 2-(3,5-dihydroxy-2-nonanoylphenyl)acetate
• 别名: Cytosporone A n-amyl ester; compound 10i

产品登记号

• MDL号: MFCD18632550

产品性质

• Empirical Formula (Hill Notation): C22H34O5
• 纯度: ≥98% (HPLC)
• 外观: white powder
• 溶解度: DMSO: >65 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 危险公开号: 22
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus.

详细说明 (简体中文)

Biochem/physiol Actions
n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus.