(E/Z)-BCI hydrochloride

• 产品号: B4313
• CAS号: 95130-23-7
• 分子式: C22H24ClNO
• 分子量: 353.88506
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: (E/Z)-BCI hydrochloride
• IUPAC标准名: 3-(cyclohexylamino)-2-(phenylmethylidene)-2,3-dihydro-1H-inden-1-one hydrochloride
• IUPAC传统名: 3-(cyclohexylamino)-2-(phenylmethylidene)-3H-inden-1-one hydrochloride
• 别名: NSC 150117 hydrochloride; (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one; 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one; 2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride

产品登记号

• MDL号: MFCD16875416
• CAS号: 95130-23-7

产品性质

• Empirical Formula (Hill Notation): C22H23NO · HCl
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: DMSO: ≥10 mg/mL
• RID/ADR: UN 3077 9/PG 3
• 保存条件: desiccated
• 保存温度: 2-8°C
• 联合国危险货物等级: 9
• 联合国危险货物编号: 3077
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.

详细说明 (简体中文)

Biochem/physiol Actions
BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.