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PHA-665752 hydrate

产品号 PZ0147 公司名称 Sigma Aldrich
CAS号 477575-56-7(anhydrous) 公司网站 http://www.sigmaaldrich.com
分子式 C32H36Cl2N4O5S 电 话 1-800-521-8956
分子量 659.62304 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 154738

产品价格信息

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产品别名

标题
PHA-665752 hydrate
IUPAC标准名
5-[(2,6-dichlorophenyl)methanesulfonyl]-3-({3,5-dimethyl-4-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1H-pyrrol-2-yl}methylidene)-2,3-dihydro-1H-indol-2-one hydrate
IUPAC传统名
5-[(2,6-dichlorophenyl)methanesulfonyl]-3-({3,5-dimethyl-4-[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl]-1H-pyrrol-2-yl}methylidene)-1H-indol-2-one hydrate
别名
(3Z)-5-[[(2,6-Dichlorophenyl)methyl]sulfonyl]-3-[[3,5-dimethyl-4-[[(2R)-2-(1-pyrrolidinylmethyl)-1-pyrrolidinyl]carbonyl]-1H-pyrrol-2-yl]methylene]-1,3-dihydro-2H-indol-2-one hydrate

产品登记号

CAS号 477575-56-7(anhydrous)
MDL号 MFCD18632554

产品性质

Empirical Formula (Hill Notation) C32H34Cl2N4O4S · xH2O
纯度 ≥98% (HPLC)
外观 light yellow to light brown powder
比旋光度 [α]/D +50 to +70°, c = 0.2 in methanol
溶解度 DMSO: ≥20 mg/mL
MSDS下载 下载链接
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-665752 ia a c-Met kinase inhibitor. PHA-665752 is ATP-competitive, an active-site inhibitor with greater than 50-fold selectivity for c-Met vs a panel of tyrosine and serine-threonine kinases.
详细说明 (简体中文)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
PHA-665752 ia a c-Met kinase inhibitor. PHA-665752 is ATP-competitive, an active-site inhibitor with greater than 50-fold selectivity for c-Met vs a panel of tyrosine and serine-threonine kinases.

参考文献