CP-802079 hydrochloride hydrate

• 产品号: PZ0148
• CAS号: 736175-49-8(freebase)
• 分子式: C22H24Cl2N2O5S
• 分子量: 499.40736
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: CP-802079 hydrochloride hydrate
• IUPAC标准名: 2-{[3-(4-chlorophenyl)-3-[4-(1,3-thiazole-2-carbonyl)phenoxy]propyl](methyl)amino}acetic acid hydrate hydrochloride
• IUPAC传统名: {[3-(4-chlorophenyl)-3-[4-(1,3-thiazole-2-carbonyl)phenoxy]propyl](methyl)amino}acetic acid hydrate hydrochloride
• 别名: N-[3-(4-Chlorophenyl)-3-[4-(2-thiazolylcarbonyl)phenoxy]propyl]-N-methyl-glycine hydrochloride hydrate; ({3-(4-Chlorophenyl)-3-[4-(thiazole-carbonyl)-phenoxy]-propyl}-methyl-amino)-acetic acid hydrochloride hydrate

产品登记号

• MDL号: MFCD18452850
• CAS号: 736175-49-8(freebase)

产品性质

• Empirical Formula (Hill Notation): C22H21ClN2O4S · xHCl · yH2O
• 纯度: ≥98% (HPLC)
• 外观: very light brown powder
• 溶解度: DMSO: ≥20 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H315-H319-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 22-36/37/38
• 安全公开号: 26
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
CP-802079 is a potent and selective glycine transporter type 1 (GlyT1) antagonist. Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, they can augment NMDAR currents and NMDAR-mediated functions. CP-802,079 significantly increases the amplitude of the NMDAR currents and LTP.

详细说明 (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
CP-802079 is a potent and selective glycine transporter type 1 (GlyT1) antagonist. Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, they can augment NMDAR currents and NMDAR-mediated functions. CP-802,079 significantly increases the amplitude of the NMDAR currents and LTP.