Olopatadine hydrochloride

• 产品号: O0391
• CAS号: 140462-76-6
• 分子式: C21H24ClNO3
• 分子量: 373.87316
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Olopatadine hydrochloride
• IUPAC标准名: 2-{2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl}acetic acid hydrochloride
• IUPAC传统名: {2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^3,^8]pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl}acetic acid hydrochloride
• 别名: (11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride; AL-4943A; KW-4679; Opatanol; Patanol

产品登记号

• CAS号: 140462-76-6
• MDL号: MFCD00875716

产品性质

• Empirical Formula (Hill Notation): C21H23NO3·HCl
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: H2O: ≥20 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301-H400
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273-P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 25-50
• 安全公开号: 45-61
• 保存温度: room temp
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Olopatadine is a histamine H1 receptor antagonist and mast cell stabilizer. The low level of occupancy H1 receptors in the brain explains the low sedation effect of olopatidine. It is believed that olopatidine is a substrate for P-glycoprotein, which limits its brain penetration.1

详细说明 (简体中文)

Biochem/physiol Actions
Olopatadine is a histamine H1 receptor antagonist and mast cell stabilizer. The low level of occupancy H1 receptors in the brain explains the low sedation effect of olopatidine. It is believed that olopatidine is a substrate for P-glycoprotein, which limits its brain penetration.1