FM19G11

• 产品号: F8807
• CAS号: 329932-55-0
• 分子式: C23H17N3O8
• 分子量: 463.39638
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: FM19G11
• IUPAC标准名: 2-(4-methylphenyl)-2-oxoethyl 3-(2,4-dinitrobenzamido)benzoate
• IUPAC传统名: 2-(4-methylphenyl)-2-oxoethyl 3-(2,4-dinitrobenzamido)benzoate
• 别名: [2-oxo-2-(p-tolyl)ethyl] 3-[(2,4-dinitrobenzoyl)amino]benzoate; 3-[(2,4-Dinitrobenzoyl)amino]-benzoic acid 2-(4-methylphenyl)-2-oxoethyl ester

产品登记号

• CAS号: 329932-55-0
• MDL号: MFCD01174289

产品性质

• Empirical Formula (Hill Notation): C23H17N3O8
• 纯度: ≥98% (HPLC)
• 外观: off-white to light brown powder
• 溶解度: DMSO: ≥40 mg/mL
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
FM19G11 is an inhibitor of Hypoxia Inducible Factors α (HIFα), reported to affect self-renewal and differentiation of stem cells. Hypoxia-inducible factors (HIFs) are transcription factors that respond to changes in available oxygen in the cellular environment. Among other functions (like angiogenesis), HIFα proteins affect the self-renewal and the differentiation processes of stem cells. FM19G11 inhibits the HIFα proteins that repress the target genes of the two α subunits, in various tumor cell lines as well as in adult and embryonic stem cell (ESC) models.

详细说明 (简体中文)

Biochem/physiol Actions
FM19G11 is an inhibitor of Hypoxia Inducible Factors α (HIFα), reported to affect self-renewal and differentiation of stem cells. Hypoxia-inducible factors (HIFs) are transcription factors that respond to changes in available oxygen in the cellular environment. Among other functions (like angiogenesis), HIFα proteins affect the self-renewal and the differentiation processes of stem cells. FM19G11 inhibits the HIFα proteins that repress the target genes of the two α subunits, in various tumor cell lines as well as in adult and embryonic stem cell (ESC) models.