Zafirlukast

• 产品号: Z4152
• CAS号: 107753-78-6
• 分子式: C31H33N3O6S
• 分子量: 575.67522
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Zafirlukast
• IUPAC标准名: cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5-yl]carbamate
• IUPAC传统名: zafirlukast
• 别名: N-[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic acid cyclopentyl ester

产品登记号

• MDL号: MFCD00864775
• CAS号: 107753-78-6

产品性质

• Empirical Formula (Hill Notation): C31H33N3O6S
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: DMSO: ≥28 mg/mL
• GHS危险声明: H413
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Zafirlukast is a potent subtype specific cysteinyl leukotriene type 1 receptor (CysLT1) antagonist; antiasthmatic. Zafirlukast has over 1000-fold selectivity for CysLT1, one of two receptors for cysteinyl leukotrienes LTC4, LTD4, and LTE4, which are important mediators of human bronchial asthma.

详细说明 (简体中文)

Biochem/physiol Actions
Zafirlukast is a potent subtype specific cysteinyl leukotriene type 1 receptor (CysLT1) antagonist; antiasthmatic. Zafirlukast has over 1000-fold selectivity for CysLT1, one of two receptors for cysteinyl leukotrienes LTC4, LTD4, and LTE4, which are important mediators of human bronchial asthma.