Acepromazine maleate

• 产品号: A7111
• CAS号: 3598-37-6
• 分子式: C23H26N2O5S
• 分子量: 442.52794
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: Acepromazine maleate
• IUPAC标准名: 1-{10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one; but-2-enedioic acid
• IUPAC传统名: Ace; butenedioic acid
• 别名: Acepromazine maleate salt; Acetopromazine maleate salt; 2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine maleate salt

产品登记号

• CAS号: 3598-37-6
• EC号: 222-748-9
• MDL号: MFCD00082473

产品性质

• Empirical Formula (Hill Notation): C19H22N2OS · C4H4O4
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: H2O: >10 mg/mL
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• RID/ADR: UN 3077 9/PG 3
• 危险公开号: 22-50/53
• RTECS编号: OB2450000
• 安全公开号: 60-61
• 保存条件: protect from light
• 保存温度: room temp
• 联合国危险货物等级: 9
• 联合国危险货物编号: 3077
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
Acepromazine is a phenothiazine and an analogue of the antipsychotic drug chlorpromazine (Cat. No. C8138). Acepromazine is thought to block dopamine receptors in the brain, and inhibit ABCG2 transport protein whose overexpression in tumors is associated with drug resistance.
Biochem/physiol Actions
Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine (#C8138). The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.

详细说明 (简体中文)

Application
Acepromazine is a phenothiazine and an analogue of the antipsychotic drug chlorpromazine (Cat. No. C8138). Acepromazine is thought to block dopamine receptors in the brain, and inhibit ABCG2 transport protein whose overexpression in tumors is associated with drug resistance.
Biochem/physiol Actions
Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine (#C8138). The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.