PHPS1 sodium salt hydrate

• 产品号: P0039
• CAS号: 314291-83-3(freeacid)
• 分子式: C21H16N5NaO7S
• 分子量: 505.43581
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: PHPS1 sodium salt hydrate
• IUPAC标准名: sodium 4-{2-[3-(4-nitrophenyl)-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}benzene-1-sulfonate hydrate
• IUPAC传统名: sodium 4-{2-[3-(4-nitrophenyl)-5-oxo-1-phenylpyrazol-4-ylidene]hydrazin-1-yl}benzenesulfonate hydrate
• 别名: 4-[2-[1,5-dihydro-3-(4-nitrophenyl)-5-oxo-1-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]-benzenesulfonic acid sodium salt hydrate

产品登记号

• CAS号: 314291-83-3(freeacid)

产品性质

• Empirical Formula (Hill Notation): C21H15N5O6S · xNa+ · yH2O
• 纯度: ≥98% (HPLC)
• 外观: red solid
• 溶解度: DMSO: soluble10 mg/mL, clear (warmed)
• 保存条件: desiccated
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Shp-2 is a Src Homology-2 (SH2) containing phosphatase that regulates growth factor signalling. The enzyme is expressed ubiquitously in mammalian tissues and plays essential roles in development. It is also implicated in various pathological states. PHPS1 is a selective inhibitor of Shp-2 and blocks Shp-2 dependent downstream signalling.

详细说明 (简体中文)

Biochem/physiol Actions
Shp-2 is a Src Homology-2 (SH2) containing phosphatase that regulates growth factor signalling. The enzyme is expressed ubiquitously in mammalian tissues and plays essential roles in development. It is also implicated in various pathological states. PHPS1 is a selective inhibitor of Shp-2 and blocks Shp-2 dependent downstream signalling.