L-365260

• 产品号: L4795
• CAS号: 118101-09-0
• 分子式: C24H24N4O
• 分子量: 384.47356
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: L-365260
• IUPAC标准名: 1-[(3R)-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea
• IUPAC传统名: 1-[(3R)-1-methyl-5-phenyl-2,3-dihydro-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea
• 别名: N-[(3R)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N′-(3-methylphenyl)-urea

产品登记号

• CAS号: 118101-09-0

产品性质

• Empirical Formula (Hill Notation): C24H22N4O2
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: DMSO: >20 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301-H400
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273-P301 + P310
• 危险公开号: 25-50/53
• 安全公开号: 45-60-61
• 保存条件: desiccated
• 保存温度: -20°C

产品详细信息

详细说明 (English)

Biochem/physiol Actions
L-365260 is a CCK2 selective antagonist. Enhances amphetamine-induced stimulation of locomotor activity in rats (a model of drug abuse), inhibits thyroid carcinoma (TT)-cell proliferation (potential therapeutic implication for cancer treatment); bilateral injection into the medulla reverses both tactile allodynia and thermal hyperalgesia.

详细说明 (简体中文)

Biochem/physiol Actions
L-365260 is a CCK2 selective antagonist. Enhances amphetamine-induced stimulation of locomotor activity in rats (a model of drug abuse), inhibits thyroid carcinoma (TT)-cell proliferation (potential therapeutic implication for cancer treatment); bilateral injection into the medulla reverses both tactile allodynia and thermal hyperalgesia.