双氯青霉素 钠盐 一水合物

• 产品号: D9016
• CAS号: 13412-64-1
• 分子式: C19H18Cl2N3NaO6S
• 分子量: 510.32349

产品别名

• 标题: Dicloxacillin sodium salt monohydrate
• IUPAC标准名: sodium (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate
• IUPAC传统名: sodium dicloxacillin(1-) hydrate

产品登记号

• EC号: 206-444-3
• PubChem SID: 24894242
• CAS号: 13412-64-1
• MDL号: MFCD00167147

产品性质

• Empirical Formula (Hill Notation): C19H16Cl2N3NaO5S·H2O
• GHS警示词: Danger
• GHS危险声明: H315-H319-H334-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338-P342 + P311
• 危险公开号: 36/37/38-42/43
• RTECS编号: XH8925000
• 安全公开号: 22-26-36/37-45
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Application
Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin. Dicloxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. It is resistant to penicillinase. It is used to study bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking and to study mechanims of penicillinase (β-lactamase) resistance. It is used to study phenylbutazone plasma binding1 and extracellular and intracellular killing of Staphylococcus aureus2
Dicloxacillin is used to study bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking and to study mechanims of penicillinase (β-lactamase) resistance.
Biochem/physiol Actions
Docloxacillin binds to specific penicillin-binding proteins (PBPs) in the bacterial cell wall and therefore inhibits the last stage of bacterial cell wall synthesis. Cell lysis, mediated by bacterial cell wall autolytic enzymes, is the result. Dicloxacillin may interfere with autolysin inhibitors .

详细说明 (简体中文)

Application
Dicloxacillin is a β-lactamase resistant penicillin similar to oxacillin. Dicloxacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. It is resistant to penicillinase. It is used to study bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking and to study mechanims of penicillinase (β-lactamase) resistance. It is used to study phenylbutazone plasma binding1 and extracellular and intracellular killing of Staphylococcus aureus2
Dicloxacillin is used to study bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking and to study mechanims of penicillinase (β-lactamase) resistance.
Biochem/physiol Actions
Docloxacillin binds to specific penicillin-binding proteins (PBPs) in the bacterial cell wall and therefore inhibits the last stage of bacterial cell wall synthesis. Cell lysis, mediated by bacterial cell wall autolytic enzymes, is the result. Dicloxacillin may interfere with autolysin inhibitors .