Zerumbone

• 产品号: Z3902
• CAS号: 471-05-6
• 分子式: C15H22O
• 分子量: 218.33458
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Zerumbone
• IUPAC标准名: 2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one
• IUPAC传统名: 2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one
• 别名: Zerumbone (6CI,7CI); (2E,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trien-1-one

产品登记号

• MDL号: MFCD03700769
• CAS号: 471-05-6

产品性质

• Empirical Formula (Hill Notation): C15H22O
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: DMSO: ≥10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H317-H400
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273-P280
• RID/ADR: UN 3077 9/PG 3
• 危险公开号: 43-50
• 安全公开号: 36/37-60-61
• 保存温度: 2-8°C
• 联合国危险货物等级: 9
• 联合国危险货物编号: 3077
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts. Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger).

详细说明 (简体中文)

Biochem/physiol Actions
Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts. Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger).