VU 590 dihydrochloride hydrate

• 产品号: V4265
• 分子式: C24H36Cl2N4O8
• 分子量: 579.47064
• 纯 度: ≥ (HPLC)
• 保 存: desiccated

产品别名

• 标题: VU 590 dihydrochloride hydrate
• IUPAC标准名: 7,13-bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane hydrate dihydrochloride
• IUPAC传统名: 7,13-bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane hydrate dihydrochloride

产品登记号

• MDL号: MFCD16875439

产品性质

• Empirical Formula (Hill Notation): C24H32N4O7·2HCl · xH2O
• 纯度: ≥ (HPLC)
• 外观: solid
• 溶解度: deionized water: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H315-H319-H335
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 22-36/37/38
• 安全公开号: 26
• 保存条件: desiccated
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
VU590 inhibits ROMK at sub-micromolar affinity (294 nM) and Kir7.1 at low micromolar affinity, but it does not inhibit Kir2.1 or Kir4.1. VU590 appears to act by blocking the ion permeation pathway of the channel.

详细说明 (简体中文)

Biochem/physiol Actions
VU590 inhibits ROMK at sub-micromolar affinity (294 nM) and Kir7.1 at low micromolar affinity, but it does not inhibit Kir2.1 or Kir4.1. VU590 appears to act by blocking the ion permeation pathway of the channel.