Osthole

• 产品号: O9265
• CAS号: 484-12-8
• 分子式: C15H16O3
• 分子量: 244.28574
• 纯 度: ≥95% (HPLC)

产品别名

• 标题: Osthole
• IUPAC标准名: 7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
• IUPAC传统名: osthole
• 别名: 7-Methoxy-8-(3-methyl-2-butenyl)coumarin; 7-Methoxy-8-isopentenylcoumarin; Osthol

产品登记号

• CAS号: 484-12-8
• MDL号: MFCD00076049

产品性质

• Empirical Formula (Hill Notation): C15H16O3
• 纯度: ≥95% (HPLC)
• 外观: white powder
• 溶解度: methanol: soluble10 mg/mL, clear, colorless
• RTECS编号: GN7700000
• 保存温度: room temp
• 德国WGK号: 1

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model.1 Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders.2 Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.3
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. O9265.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

详细说明 (English)

Biochem/physiol Actions
Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model.1 Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders.2 Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.3
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. O9265.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.