Fasentin

• 产品号: F5557
• CAS号: 392721-37-8
• 分子式: C11H9ClF3NO2
• 分子量: 279.6428696
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Fasentin
• IUPAC标准名: N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
• IUPAC传统名: N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
• 别名: N-[4-Chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide

产品登记号

• CAS号: 392721-37-8
• MDL号: MFCD01001285

产品性质

• Empirical Formula (Hill Notation): C11H9ClF3NO2
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: DMSO: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 危险公开号: 22
• 保存温度: room temp
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Fasentin is a novel inhibitor of glucose uptake, GluT1 inhibitor. Fasentin is a novel inhibitor of glucose uptake that sensitizes cells to FAS-induced cell death. Fasentin selectively sensitized to death ligands, but did not decrease FLIP expression. It alters expression of genes associated with nutrient and glucose deprivation. Fasentin interacted with a unique site in the intracellular channel of the glucose transport protein GLUT1.

详细说明 (简体中文)

Biochem/physiol Actions
Fasentin is a novel inhibitor of glucose uptake, GluT1 inhibitor. Fasentin is a novel inhibitor of glucose uptake that sensitizes cells to FAS-induced cell death. Fasentin selectively sensitized to death ligands, but did not decrease FLIP expression. It alters expression of genes associated with nutrient and glucose deprivation. Fasentin interacted with a unique site in the intracellular channel of the glucose transport protein GLUT1.