CP-471474

• 产品号: PZ0137
• CAS号: 210755-45-6
• 分子式: C16H17FN2O5S
• 分子量: 368.3799832
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: CP-471474
• IUPAC标准名: 2-[4-(4-fluorophenoxy)benzenesulfonamido]-N-hydroxy-2-methylpropanamide
• IUPAC传统名: 2-[4-(4-fluorophenoxy)benzenesulfonamido]-N-hydroxy-2-methylpropanamide
• 别名: PF-1626077; 2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydrox y-2-methylpropanamide

产品登记号

• CAS号: 210755-45-6
• MDL号: MFCD16618408

产品性质

• Empirical Formula (Hill Notation): C16H17FN2O5S
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: DMSO: ≥20 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 危险公开号: 22
• 保存温度: room temp
• 德国WGK号: 1

产品详细信息

详细说明 (English)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
CP-471474 is a broad spectrum inhibitor of matrix metalloproteinases. CP-471474 has a low nM IC50 efficacy for MMP-2, MMP-3, MMP-9, and MMP-13. CP-471474 has low potency against MMP-1 (IC50 > 1 uM). CP-471474 prevents left ventricular remodeling after experimental myocardial infarction in mice. CP-471474 also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models.

详细说明 (简体中文)

Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
CP-471474 is a broad spectrum inhibitor of matrix metalloproteinases. CP-471474 has a low nM IC50 efficacy for MMP-2, MMP-3, MMP-9, and MMP-13. CP-471474 has low potency against MMP-1 (IC50 > 1 uM). CP-471474 prevents left ventricular remodeling after experimental myocardial infarction in mice. CP-471474 also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models.