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Atorvastatin calcium salt trihydrate

产品号 PZ0001 公司名称 Sigma Aldrich
CAS号 134523-03-8(anhydrous) 公司网站 http://www.sigmaaldrich.com
分子式 C66H74CaF2N4O13 电 话 1-800-521-8956
分子量 1209.3875664 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 protect from light Chembase数据库ID: 154585

产品价格信息

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产品别名

标题
Atorvastatin calcium salt trihydrate
IUPAC标准名
trihydrate {[(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoyl]oxy}calcio (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
IUPAC传统名
trihydrate {[(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoyl]oxy}calcio (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoate

产品登记号

MDL号 MFCD09752074
CAS号 134523-03-8(anhydrous)

产品性质

Empirical Formula (Hill Notation) C33H34FN2O5 · 0.5 Ca · 1.5 H2O
纯度 ≥98% (HPLC)
外观 white powder
溶解度 DMSO: ≥10 mg/mL
MSDS下载 下载链接
保存条件 protect from light
保存温度 room temp
德国WGK号 3

产品详细信息

详细说明 (English)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Atorvastatin calcium salt trihydrate is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.
详细说明 (简体中文)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
Atorvastatin calcium salt trihydrate is a specific inhibitor of HMG-CoA reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.

参考文献