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NVP-231

产品号 N9289 公司名称 Sigma Aldrich
CAS号 362003-83-6 公司网站 http://www.sigmaaldrich.com
分子式 C25H25N3O2S 电 话 1-800-521-8956
分子量 431.5499 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 154575

产品价格信息

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产品别名

标题
NVP-231
IUPAC标准名
(3R,5S,7s)-N-(2-benzamido-1,3-benzothiazol-6-yl)adamantane-1-carboxamide
IUPAC传统名
(3R,5S,7s)-N-(2-benzamido-1,3-benzothiazol-6-yl)adamantane-1-carboxamide
别名
N-[2-(benzoylamino)-6-benzothiazolyl]-Tricyclo[3.3.1.13,7]decane-1-carboxamide
adamantane-1-carboxylic acid (2-benzoylamino-benzothiazol-6-yl)amide

产品登记号

CAS号 362003-83-6
MDL号 MFCD01988824

产品性质

Empirical Formula (Hill Notation) C25H25N3O2S
纯度 ≥98% (HPLC)
外观 white to off-white powder
溶解度 DMSO: >10 mg/mL
MSDS下载 下载链接
保存温度 2-8°C
德国WGK号 nwg

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Ceramide kinase presents an attractive target for drug development because of its involvement in cell growth and inflammation. CerK biology is still poorly understood thus discovery and availability of inhibitors will facilitate research at this area. NVP-231 is a newly discovered potent, specific and reversible CerK inhibitor that competitively inhibits binding of ceraminde to CerK.
详细说明 (简体中文)
Biochem/physiol Actions
Ceramide kinase presents an attractive target for drug development because of its involvement in cell growth and inflammation. CerK biology is still poorly understood thus discovery and availability of inhibitors will facilitate research at this area. NVP-231 is a newly discovered potent, specific and reversible CerK inhibitor that competitively inhibits binding of ceraminde to CerK.

参考文献