Bendamustine hydrochloride hydrate

• 产品号: B5437
• 分子式: C16H24Cl3N3O3
• 分子量: 412.73906
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Bendamustine hydrochloride hydrate
• IUPAC标准名: 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid hydrate hydrochloride
• IUPAC传统名: bendamustine hydrate hydrochloride
• 别名: Treanda; 1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl monohydrochloride

产品登记号

• MDL号: MFCD16879055

产品性质

• Empirical Formula (Hill Notation): C16H21Cl2N3O2·HCl · xH2O
• 纯度: ≥98% (HPLC)
• 外观: off-white powder
• 溶解度: H2O: >30 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301-H351-H360
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P201-P281-P301 + P310-P308 + P313
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 60-61-22-40
• RTECS编号: DE1590000
• 安全公开号: 36-37
• 保存温度: room temp
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Bendamustine hydrochloride is a DNA-alkylator with a distinct pattern of activity. Bendamustine activates DNA-damage stress response and apoptosis; inhibits mitotic checkpoints; and induces mitotic catastrophe.

详细说明 (简体中文)

Biochem/physiol Actions
Bendamustine hydrochloride is a DNA-alkylator with a distinct pattern of activity. Bendamustine activates DNA-damage stress response and apoptosis; inhibits mitotic checkpoints; and induces mitotic catastrophe.