NBI-31772 hydrate

• 产品号: N8289
• CAS号: 374620-70-9(anhydrous)
• 分子式: C17H13NO8
• 分子量: 359.28702
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: NBI-31772 hydrate
• IUPAC标准名: 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid hydrate
• IUPAC传统名: 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid hydrate

产品登记号

• CAS号: 374620-70-9(anhydrous)
• MDL号: MFCD20274527

产品性质

• Empirical Formula (Hill Notation): C17H11NO7 · xH2O
• 纯度: ≥98% (HPLC)
• 外观: solid
• 保存条件: protect from light
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
NBI-31772 is an insulin-like growth factor-1 binding proteins (IGFBPs) inhibitor; IGF-1 potentiator. NBI-31772 is an air/DMSO DOPA oxidation product, which inhibits IGF binding to IFGFB′s. NBI-31772 displaces IGF-1 from IGF1:IGFBP complex. Thus, it increases circulating level of IGF-1. NBI-31772 does not bind to IGFR.

详细说明 (简体中文)

Biochem/physiol Actions
NBI-31772 is an insulin-like growth factor-1 binding proteins (IGFBPs) inhibitor; IGF-1 potentiator. NBI-31772 is an air/DMSO DOPA oxidation product, which inhibits IGF binding to IFGFB′s. NBI-31772 displaces IGF-1 from IGF1:IGFBP complex. Thus, it increases circulating level of IGF-1. NBI-31772 does not bind to IGFR.