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S-2E

产品号 S6445 公司名称 Sigma Aldrich
CAS号 155730-92-0 公司网站 http://www.sigmaaldrich.com
分子式 C22H25NO4 电 话 1-800-521-8956
分子量 367.4382 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 154538

产品价格信息

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产品别名

标题
S-2E
IUPAC标准名
4-{[(3S)-1-(4-tert-butylphenyl)-5-oxopyrrolidin-3-yl]methoxy}benzoic acid
IUPAC传统名
4-{[(3S)-1-(4-tert-butylphenyl)-5-oxopyrrolidin-3-yl]methoxy}benzoic acid
别名
(S)-(+)-4-[1-(4-tert-Butylphenyl)-2-oxo-pyrrolidin-4-yl]methoxybenzoic acid

产品登记号

PubChem SID 24724620
MDL号 MFCD06407742
CAS号 155730-92-0

产品性质

Empirical Formula (Hill Notation) C22H25NO4
纯度 ≥98% (HPLC)
外观 white powder
溶解度 DMSO: soluble11 mg/mL
溶解度 H2O: insoluble
MSDS下载 下载链接
个人保护装置 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度 -20°C
德国WGK号 3

产品详细信息

详细说明 (English)
Packaging
Shipped ambient under nitrogen.
Biochem/physiol Actions
HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. In the liver, S-2E is converted into its active metabolite, S-2E-CoA. S-2E-CoA noncompetitively inhibited the enzymatic activities of both 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductase and acetyl-CoA carboxylase at K(i)=18.11 microM and K(i)=69.2 microM, respectively.
详细说明 (简体中文)
包装
Shipped ambient under nitrogen.
Biochem/physiol Actions
HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. In the liver, S-2E is converted into its active metabolite, S-2E-CoA. S-2E-CoA noncompetitively inhibited the enzymatic activities of both 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductase and acetyl-CoA carboxylase at K(i)=18.11 microM and K(i)=69.2 microM, respectively.

参考文献