S32826 disodium salt hydrate

• 产品号: S1825
• CAS号: 1096770-84-1(freeacid)
• 分子式: C21H34NNa2O4P
• 分子量: 441.452261
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: S32826 disodium salt hydrate
• IUPAC标准名: disodium [(4-tetradecanamidophenyl)methyl]phosphonate
• IUPAC传统名: disodium (4-tetradecanamidophenyl)methylphosphonate
• 别名: [4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt hydrate

产品登记号

• MDL号: MFCD12912442
• CAS号: 1096770-84-1(freeacid)

产品性质

• Empirical Formula (Hill Notation): C21H34NNa2O4P · xH2O
• 纯度: ≥98% (HPLC)
• 外观: white powder
• 溶解度: H2O: ≥10 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存条件: desiccated
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
S32826 is a potent inhibitor of autotaxin. Autotaxin is a newly discovered lyso-phospholipase D (lysoPLD). Autotaxin and lyso-phosphatidic acid (LPA) have been associated with early cancer progression and motility of cancer cells as well as with metastasis. Because of localization (adipose tissue), the enzyme might play an important role in diabetes and obesity. Autotaxin might be the only source of LPA. S32826 is the strongest inhibitor of autotaxin reported. The compound shows activity in cellular or ex vivo models.

详细说明 (简体中文)

Biochem/physiol Actions
S32826 is a potent inhibitor of autotaxin. Autotaxin is a newly discovered lyso-phospholipase D (lysoPLD). Autotaxin and lyso-phosphatidic acid (LPA) have been associated with early cancer progression and motility of cancer cells as well as with metastasis. Because of localization (adipose tissue), the enzyme might play an important role in diabetes and obesity. Autotaxin might be the only source of LPA. S32826 is the strongest inhibitor of autotaxin reported. The compound shows activity in cellular or ex vivo models.