LWH-63 hydrochloride

• 产品号: L9167
• CAS号: 276890-57-4
• 分子式: C24H35ClN4O
• 分子量: 431.0139
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: LWH-63 hydrochloride
• IUPAC标准名: 4-{ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}butan-1-ol hydrochloride
• IUPAC传统名: 4-{ethyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amino}butan-1-ol hydrochloride
• 别名: 4-(N-Ethyl-n-4-hydroxybutyl)amino-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidine hydrochloride; NIH-3

产品登记号

• PubChem SID: 24724529
• CAS号: 276890-57-4
• MDL号: MFCD07784506

产品性质

• Empirical Formula (Hill Notation): C24H35ClN4O
• 纯度: ≥98% (HPLC)
• 外观: light brown solid
• 溶解度: DMSO: ~10 mg/mL
• 溶解度: H2O: insoluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Non-peptide CRF1 corticotrophin-releasing factor antagonist. Ki = 0.68 nM; blocks ethanol-induced effects as well as CRF effects in mice, suggesting a possible therapeutic target for the treatment of stress-induced alcohol drinking.

详细说明 (简体中文)

Biochem/physiol Actions
Non-peptide CRF1 corticotrophin-releasing factor antagonist. Ki = 0.68 nM; blocks ethanol-induced effects as well as CRF effects in mice, suggesting a possible therapeutic target for the treatment of stress-induced alcohol drinking.