Bicyclol

• 产品号: B3313
• CAS号: 118159-48-1
• 分子式: C19H18O9
• 分子量: 390.34082
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: Bicyclol
• IUPAC标准名: methyl 4-[5-(hydroxymethyl)-7-methoxy-2H-1,3-benzodioxol-4-yl]-7-methoxy-2H-1,3-benzodioxole-5-carboxylate
• IUPAC传统名: methyl 4-[5-(hydroxymethyl)-7-methoxy-2H-1,3-benzodioxol-4-yl]-7-methoxy-2H-1,3-benzodioxole-5-carboxylate
• 别名: 4, 4′-dimethoxy-2, 3, 2′, 3′-bis(methylenedioxy)-6-hydroxymethyl-6′-methoxy-carbonyl biphenyl

产品登记号

• MDL号: MFCD00889471
• CAS号: 118159-48-1

产品性质

• Empirical Formula (Hill Notation): C19H18O9
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: DMSO: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H400
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P273
• 危险公开号: 50/53
• RTECS编号: DT4312000
• 安全公开号: 60-61
• 保存条件: desiccated
• 保存温度: 2-8°C

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C. The drug appears to protect against liver injury in animals. Recently it was reported that bicyclol induce the expression of hepatic HSP27 and HSP70, and thus consequently inhibits the transcription factor NF-?B-mediated apoptosis and necrosis in liver tissue. It appears that bicyclol induces hepatic HSP27 and HSP70 expression through activating transcription of HSPs genes.

详细说明 (简体中文)

Biochem/physiol Actions
Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C. The drug appears to protect against liver injury in animals. Recently it was reported that bicyclol induce the expression of hepatic HSP27 and HSP70, and thus consequently inhibits the transcription factor NF-?B-mediated apoptosis and necrosis in liver tissue. It appears that bicyclol induces hepatic HSP27 and HSP70 expression through activating transcription of HSPs genes.