Ro4368554

• 产品号: R8782
• CAS号: 478082-99-4
• 分子式: C19H21N3O2S
• 分子量: 355.45394
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Ro4368554
• IUPAC标准名: 3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
• IUPAC传统名: 3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
• 别名: 3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole; 7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole

产品登记号

• CAS号: 478082-99-4
• MDL号: MFCD16875430

产品性质

• Empirical Formula (Hill Notation): C19H21N3O2S
• 纯度: ≥98% (HPLC)
• 外观: off-white powder
• 溶解度: DMSO: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 危险公开号: 22
• 保存温度: room temp
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).

详细说明 (简体中文)

Biochem/physiol Actions
Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).