Tandospirone

• 产品号: T6704
• CAS号: 87760-53-0
• 分子式: C21H29N5O2
• 分子量: 383.48726
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: Tandospirone
• IUPAC标准名: (1R,2S,6R,7S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-4-azatricyclo[5.2.1.0^2,^6]decane-3,5-dione
• IUPAC传统名: tandospirone
• 别名: (1R*,2S*,3R*,4S*)-N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-2,3-norbornanedicarboximide citrate salt; SM 3997

产品登记号

• CAS号: 87760-53-0

产品性质

• Empirical Formula (Hill Notation): C21H29N5O2
• 纯度: ≥98% (HPLC)
• 溶解度: DMSO: soluble38 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26
• 保存条件: protect from light
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Tandospirone is a partial agonist at 5HT1A receptors. It significantly reduces haloperidol-induced bradykinesia in a dose-dependent manner. The potency of tandospirone is equal to that of buspirone and approximate half that of diazepam. The potency of tandospirone as a dopamine antagonistic is less than 1/4 that of buspirone.

详细说明 (简体中文)

Biochem/physiol Actions
Tandospirone is a partial agonist at 5HT1A receptors. It significantly reduces haloperidol-induced bradykinesia in a dose-dependent manner. The potency of tandospirone is equal to that of buspirone and approximate half that of diazepam. The potency of tandospirone as a dopamine antagonistic is less than 1/4 that of buspirone.