BSc3094 monohydrobromide

• 产品号: B7937
• 分子式: C17H13BrN6O3S
• 分子量: 461.29252
• 纯 度: ≥98% (HPLC)
• 保 存: protect from light

产品别名

• 标题: BSc3094 monohydrobromide
• IUPAC标准名: N'-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]-1H-1,3-benzodiazole-5-carbohydrazide hydrobromide
• IUPAC传统名: N'-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]-1H-1,3-benzodiazole-5-carbohydrazide hydrobromide
• 别名: 2-[4-(4-Nitrophenyl)-2-thiazolyl]hydrazide-1H-benzimidazole-6-carboxylic acid monohydrobromide

产品登记号

• MDL号: MFCD12912398

产品性质

• Empirical Formula (Hill Notation): C17H12N6O3S·HBr
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: DMSO: soluble22 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H319
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS警示性声明: P305 + P351 + P338
• 危险公开号: 22-36
• 安全公开号: 26
• 保存条件: protect from light
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
BSc3094 is a potent inhibitor of tau aggregation and dissolves preformed tau paired helical filaments. BSc3094 interacts closely with the tau protein at the edge involving protons I-IV, while the second attachment site seems to be at the nitro group. In N2A cells (model system for tau aggregation), BSc3094 exhibited low toxicity.

详细说明 (简体中文)

Biochem/physiol Actions
BSc3094 is a potent inhibitor of tau aggregation and dissolves preformed tau paired helical filaments. BSc3094 interacts closely with the tau protein at the edge involving protons I-IV, while the second attachment site seems to be at the nitro group. In N2A cells (model system for tau aggregation), BSc3094 exhibited low toxicity.