LY2033298

• 产品号: L9919
• 分子式: C13H14ClN3O2S
• 分子量: 311.78716
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: LY2033298
• IUPAC标准名: 3-amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
• IUPAC传统名: 3-amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
• 别名: 3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methyl-thieno[2,3-b]pyridine-2-carboxamide

产品登记号

• MDL号: MFCD12912423

产品性质

• Empirical Formula (Hill Notation): C13H14ClN3O2S
• 纯度: ≥98% (HPLC)
• 外观: off-white to tan solid
• 溶解度: DMSO: >20 mg/mL
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 危险公开号: 43
• 安全公开号: 36/37
• 保存条件: desiccated
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
LY2033298 is a robust allosteric potentiator that is highly selective for the human M4 muscarinic acetylcholine receptor subtype. LY2033298 potentiates ACh-M4 binding, with no effect at M1/3/5 receptors. LY2033298 can also bind to the M ACh receptor, and mediate either positive or negative allosteric effects depending on the ligand used to probe receptor activity.1

详细说明 (简体中文)

Biochem/physiol Actions
LY2033298 is a robust allosteric potentiator that is highly selective for the human M4 muscarinic acetylcholine receptor subtype. LY2033298 potentiates ACh-M4 binding, with no effect at M1/3/5 receptors. LY2033298 can also bind to the M ACh receptor, and mediate either positive or negative allosteric effects depending on the ligand used to probe receptor activity.1