PalGly

• 产品号: P0064
• CAS号: 2441-41-0
• 分子式: C18H35NO3
• 分子量: 313.4754
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: PalGly
• IUPAC标准名: 2-hexadecanamidoacetic acid
• IUPAC传统名: N-palmitoyl glycine
• 别名: N-palmitoyl glycine; Hexadecanoylaminoacetic acid

产品登记号

• MDL号: MFCD00153471
• CAS号: 2441-41-0

产品性质

• Empirical Formula (Hill Notation): C18H35NO3
• 纯度: ≥98% (HPLC)
• 外观: white to off-white solid
• 溶解度: DMSO: >10 mg/mL
• 个人保护装置: Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
• 保存温度: 2-8°C
• 德国WGK号: 2

产品详细信息

详细说明 (English)

Biochem/physiol Actions
PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

详细说明 (简体中文)

Biochem/physiol Actions
PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.