BAY 41-2272

• 产品号: B8810
• 分子式: C20H17FN6
• 分子量: 360.3875832
• 纯 度: ≥97% (HPLC)

产品别名

• 标题: BAY 41-2272
• IUPAC标准名: 5-cyclopropyl-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-4-amine
• IUPAC传统名: 5-cyclopropyl-2-{1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-4-amine
• 别名: 3-(4-Amino-5-cyclopropylpyrimidin-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine

产品登记号

• PubChem SID: 24892096
• MDL号: MFCD06411391

产品性质

• Empirical Formula (Hill Notation): C20H17FN6
• 纯度: ≥97% (HPLC)
• 外观: white powder
• 熔点: 210.5-211.4 °C
• 溶解度: DMSO: soluble26 mg/mL at 60 °C
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
BAY 41-2272 is an activator of soluble guanylate cyclase at a novel, NO-independent regulatory site. BAY 41-2272 is the first product that stimulates sGC through a non-NO mechanism. BAY 41-2272 inhibits platelet aggregation and induces vasorelaxation without nitrate tolerance.

详细说明 (简体中文)

Biochem/physiol Actions
BAY 41-2272 is an activator of soluble guanylate cyclase at a novel, NO-independent regulatory site. BAY 41-2272 is the first product that stimulates sGC through a non-NO mechanism. BAY 41-2272 inhibits platelet aggregation and induces vasorelaxation without nitrate tolerance.