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Eplerenone

产品号 E6657 公司名称 Sigma Aldrich
CAS号 107724-20-9 公司网站 http://www.sigmaaldrich.com
分子式 C24H30O6 电 话 1-800-521-8956
分子量 414.4914 传 真
纯 度 ≥98% (HPLC) 电子邮件
保 存 Chembase数据库ID: 154403

产品价格信息

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产品别名

标题
Eplerenone
IUPAC标准名
methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.01,17.02,7.011,15]octadecan]-6'-ene-9'-carboxylate
IUPAC传统名
eplerenone
别名
9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, methyl ester
SC-66110
Inspra
Cgp 30083
HSDB 7522
Eplerenone [USAN]
Epoxymexrenone
Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)-

产品登记号

CAS号 107724-20-9

产品性质

Empirical Formula (Hill Notation) C24H30O6
纯度 ≥98% (HPLC)
外观 white to beige powder
溶解度 DMSO: soluble2 mg/mL, clear (warmed)
溶解度 H2O: insoluble
MSDS下载 下载链接
个人保护装置 Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Biochem/physiol Actions
Eplerenone is an aldosterone antagonist more specific for the mineralocorticoid receptor than spironolactone (S3378), having lower affinity for progesterone, androgen, and glucocorticoid receptors.
详细说明 (简体中文)
Biochem/physiol Actions
Eplerenone is an aldosterone antagonist more specific for the mineralocorticoid receptor than spironolactone (S3378), having lower affinity for progesterone, androgen, and glucocorticoid receptors.

参考文献