Dimebon dihydrochloride hydrate

• 产品号: D6196
• CAS号: 97657-92-6(anhydrous)
• 分子式: C21H29Cl2N3O
• 分子量: 410.38046
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Dimebon dihydrochloride hydrate
• IUPAC标准名: 5-(2-{2,8-dimethyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl}ethyl)-2-methylpyridine hydrate dihydrochloride
• IUPAC传统名: latrepirdine hydrate dihydrochloride
• 别名: Dimebolin dihydrochloride hydrate; Dimebone dihydrochloride hydrate; 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate; Dimeboline dihydrochloride hydrate

产品登记号

• MDL号: MFCD17215933
• CAS号: 97657-92-6(anhydrous)

产品性质

• Empirical Formula (Hill Notation): C21H25N3 · 2HCl · xH2O
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: H2O: ≥10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H315-H319
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• GHS警示性声明: P305 + P351 + P338
• 危险公开号: 22-36/38
• 安全公开号: 26-36/39
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Mechanism of neuroprotection and cognition enhancement is not certain, but Dimebon blocks both cholinesterase and the NMDA receptor simultaneously and also appears to block the action of neurotoxic β-amyloid proteins and inhibit L-type calcium channels, and may exert a neuroprotective effect by blocking a novel target that involves mitochondrial pores.

详细说明 (简体中文)

Biochem/physiol Actions
Mechanism of neuroprotection and cognition enhancement is not certain, but Dimebon blocks both cholinesterase and the NMDA receptor simultaneously and also appears to block the action of neurotoxic β-amyloid proteins and inhibit L-type calcium channels, and may exert a neuroprotective effect by blocking a novel target that involves mitochondrial pores.