HC-030031

• 产品号: H4415
• CAS号: 349085-38-7
• 分子式: C18H21N5O3
• 分子量: 355.39104
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: HC-030031
• IUPAC标准名: 2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)-N-[4-(propan-2-yl)phenyl]acetamide
• IUPAC传统名: 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-(4-isopropylphenyl)acetamide
• 别名: 1,2,3,6-Tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetamide; 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide

产品登记号

• MDL号: MFCD02007349
• CAS号: 349085-38-7

产品性质

• Empirical Formula (Hill Notation): C18H21N5O3
• 纯度: ≥98% (HPLC)
• 外观: off-white powder
• 溶解度: DMSO: soluble30 mg/mL
• GHS警示词: Danger
• GHS危险声明: H301
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 个人保护装置: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS警示性声明: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• 危险公开号: 25
• 安全公开号: 45
• 保存温度: room temp
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: 2811
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
HC-030031 is a selective TRPA1 channel blocker, antagonizing formalin-evoked calcium influx and formalin-induced pain. IC50 is 5 μM. TRPA1 antagonism is a promising therapeutic target for chronic inflammatory or neurogenic pain.1
HC-030031 is a selective TRPA1 channel blocker. HC-030031 antagonizes formalin-evoked calcium influx. IC50 is 5 μM.

详细说明 (简体中文)

Biochem/physiol Actions
HC-030031 is a selective TRPA1 channel blocker, antagonizing formalin-evoked calcium influx and formalin-induced pain. IC50 is 5 μM. TRPA1 antagonism is a promising therapeutic target for chronic inflammatory or neurogenic pain.1
HC-030031 is a selective TRPA1 channel blocker. HC-030031 antagonizes formalin-evoked calcium influx. IC50 is 5 μM.