GW583340 dihydrochloride

• 产品号: G3545
• 分子式: C28H27Cl3FN5O3S2
• 分子量: 671.0330832
• 纯 度: ≥97% (HPLC)

产品别名

• 标题: GW583340 dihydrochloride
• IUPAC标准名: N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)quinazolin-4-amine dihydrochloride
• IUPAC传统名: N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(2-{[(2-methanesulfonylethyl)amino]methyl}-1,3-thiazol-4-yl)quinazolin-4-amine dihydrochloride
• 别名: 4-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenylamino]-6-[2-[[2-(methylsulfonyl)ethyl]aminomethyl]-4-thiazolyl]quinazoline dihydrochloride

产品登记号

• MDL号: MFCD07370137
• PubChem SID: 24895131

产品性质

• Empirical Formula (Hill Notation): C28H25ClFN5O3S2 · 2HCl
• 纯度: ≥97% (HPLC)
• 外观: solid
• 熔点: 259.8-262.4 °C(lit.)
• 溶解度: DMSO: soluble9 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Potent dual ErbB-2/EGFR tyrosine kinase inhibitor. IC50= 0.01 and 0.014 μM for EGFR and ErbB-2. Orally active.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline

详细说明 (简体中文)

Biochem/physiol Actions
Potent dual ErbB-2/EGFR tyrosine kinase inhibitor. IC50= 0.01 and 0.014 μM for EGFR and ErbB-2. Orally active.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline