BAY 61-3606 hydrochloride hydrate

• 产品号: B9685
• 分子式: C20H21ClN6O4
• 分子量: 444.87154
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: BAY 61-3606 hydrochloride hydrate
• IUPAC标准名: 2-{[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino}pyridine-3-carboxamide hydrate hydrochloride
• IUPAC传统名: 2-{[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino}pyridine-3-carboxamide hydrate hydrochloride
• 别名: 2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide hydrochloride

产品性质

• Empirical Formula (Hill Notation): C20H18N6O3 · xHCl · yH2O
• 纯度: ≥98% (HPLC)
• 外观: yellow powder
• 溶解度: H2O: soluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Spleen tyrosine kinase (Syk) inhibitor; anti-inflammatory. Syk plays a major role in inflammation pathways via receptors for the Fc portion of immunoglobulins, as well as B cell signaling. It is orally active, potent (Ki 7.5 nM), and highly selective for Syk vs other kinases (Lyn, Fyn, Src, Itk, Btk; Ki′s).

详细说明 (简体中文)

Biochem/physiol Actions
Spleen tyrosine kinase (Syk) inhibitor; anti-inflammatory. Syk plays a major role in inflammation pathways via receptors for the Fc portion of immunoglobulins, as well as B cell signaling. It is orally active, potent (Ki 7.5 nM), and highly selective for Syk vs other kinases (Lyn, Fyn, Src, Itk, Btk; Ki′s).