ARC 239 dihydrochloride hydrate

• 产品号: A5736
• CAS号: 67339-62-2(freebase)
• 分子式: C24H33Cl2N3O4
• 分子量: 498.44252
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: ARC 239 dihydrochloride hydrate
• IUPAC标准名: 2-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione hydrate dihydrochloride
• IUPAC传统名: 2-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-4,4-dimethylisoquinoline-1,3-dione hydrate dihydrochloride
• 别名: (2-[2-[4-(o-Methoxyphenyl)piperazin-1-yl]ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolinedione dihydrochloride hydrate

产品登记号

• CAS号: 67339-62-2(freebase)
• MDL号: MFCD16875414

产品性质

• Empirical Formula (Hill Notation): C24H29N3O3·2HCl · xH2O
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: H2O: >5 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302-H400
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273
• RID/ADR: UN 3077 9/PG 3
• 危险公开号: 22-50/53
• 安全公开号: 60-61
• 保存温度: 2-8°C
• 联合国危险货物等级: 9
• 联合国危险货物编号: 3077
• 联合国危险货物包装类别(PG): 3
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Application
ARC 239 is a potent α-adrenoceptor blocking drug, competitively antagonizing pressor responses to adrenaline and inhibiting pressor responses to noradrenaline, phenylephrine, tyramine, and dimethylphenylpiperazinium.
Biochem/physiol Actions
ARC 239 is a selective α-2B adrenergic blocker. Although ARC-239, like prazosin, also has some alpha-1 antagonist activity, it is used most commomly to differentiate alpha-2A/D from alpha-2B and alpha-2C subtypes rather than for any alpha-1 inhibition..

详细说明 (简体中文)

Application
ARC 239 is a potent α-adrenoceptor blocking drug, competitively antagonizing pressor responses to adrenaline and inhibiting pressor responses to noradrenaline, phenylephrine, tyramine, and dimethylphenylpiperazinium.
Biochem/physiol Actions
ARC 239 is a selective α-2B adrenergic blocker. Although ARC-239, like prazosin, also has some alpha-1 antagonist activity, it is used most commomly to differentiate alpha-2A/D from alpha-2B and alpha-2C subtypes rather than for any alpha-1 inhibition..