BD 1047 dihydrobromide

• 产品号: B8562
• CAS号: 138356-21-5
• 分子式: C13H22Br2Cl2N2
• 分子量: 437.04118
• 纯 度: ≥95% (HPLC)

产品别名

• 标题: BD 1047 dihydrobromide
• IUPAC标准名: [2-(3,4-dichlorophenyl)ethyl][2-(dimethylamino)ethyl]methylamine dihydrobromide
• IUPAC传统名: [2-(3,4-dichlorophenyl)ethyl][2-(dimethylamino)ethyl]methylamine dihydrobromide
• 别名: BD 1047 dihydrobromide

产品登记号

• MDL号: MFCD00792739
• CAS号: 138356-21-5

产品性质

• Empirical Formula (Hill Notation): C13H20Cl2N2 · 2 HBr
• 纯度: ≥95% (HPLC)
• 外观: white powder
• 溶解度: H2O: >5 mg/mL
• GHS警示词: Danger
• GHS危险声明: H315-H318-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P280-P305 + P351 + P338
• 危险公开号: 37/38-41
• 安全公开号: 26-36/37
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
BD-1047 is a selective, putative σ receptor antagonist with antidystonic activity. BD-1047 has >50-fold selectivity at σ1 over σ2 and also >100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, α1- & α2-adrenoceptor, 5-HT1, and 5-HT2. Though s receptor antagonism is consistent with antipsychotic, especially anti-schizophrenic, activity, BD-1047 shows only modest activity in animal screens for antipsychotics.1

详细说明 (简体中文)

Biochem/physiol Actions
BD-1047 is a selective, putative σ receptor antagonist with antidystonic activity. BD-1047 has >50-fold selectivity at σ1 over σ2 and also >100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, α1- & α2-adrenoceptor, 5-HT1, and 5-HT2. Though s receptor antagonism is consistent with antipsychotic, especially anti-schizophrenic, activity, BD-1047 shows only modest activity in animal screens for antipsychotics.1