FTI-277 trifluoroacetate salt

• 产品号: F9803
• CAS号: 170006-73-2(freebase)
• 分子式: C24H30F3N3O5S2
• 分子量: 561.6373096
• 纯 度: ≥95% (HPLC)
• 保 存: desiccated

产品别名

• 标题: FTI-277 trifluoroacetate salt
• IUPAC标准名: trifluoroacetic acid methyl (2S)-2-[(4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-phenylphenyl)formamido]-4-(methylsulfanyl)butanoate
• IUPAC传统名: trifluoroacetic acid methyl (2S)-2-[(4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-phenylphenyl)formamido]-4-(methylsulfanyl)butanoate
• 别名: N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt

产品登记号

• MDL号: MFCD06795840
• CAS号: 170006-73-2(freebase)

产品性质

• Empirical Formula (Hill Notation): C22H29N3O3S2 · xC2HF3O2
• 纯度: ≥95% (HPLC)
• 运输包装: wet ice
• 外观: amorphous semi-solid
• 溶解度: H2O: ≥2 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存条件: desiccated
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Highly potent (pM/nM) Ras CAAX peptidomimetic which antagonizes both H and K-Ras oncogenic signaling. Inhibitor of farnesyltransferase (Ftase) IC50 = 50 nM.
Packaging
Very hygroscopic material, package in a dry room with deoxygenated MeOH and pump down the solvent. Store with desiccant.

详细说明 (简体中文)

Biochem/physiol Actions
Highly potent (pM/nM) Ras CAAX peptidomimetic which antagonizes both H and K-Ras oncogenic signaling. Inhibitor of farnesyltransferase (Ftase) IC50 = 50 nM.
包装
Very hygroscopic material, package in a dry room with deoxygenated MeOH and pump down the solvent. Store with desiccant.