GGTI 298 trifluoroacetate salt hydrate

• 产品号: G5169
• CAS号: 1217457-86-7(anhydrous)
• 分子式: C29H34F3N3O5S
• 分子量: 593.6575696
• 纯 度: ≥90% (HPLC)

产品别名

• 标题: GGTI 298 trifluoroacetate salt hydrate
• IUPAC标准名: trifluoroacetic acid methyl (2S)-2-[(4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-(naphthalen-1-yl)phenyl)formamido]-4-methylpentanoate
• IUPAC传统名: trifluoroacetic acid methyl (2S)-2-[(4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-(naphthalen-1-yl)phenyl)formamido]-4-methylpentanoate
• 别名: N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt hydrate

产品登记号

• PubChem SID: 24724490
• MDL号: MFCD06409252
• CAS号: 1217457-86-7(anhydrous)

产品性质

• Empirical Formula (Hill Notation): C27H33N3O3S · C2HF3O2 · xH2O
• 杂质: <10% dimer
• 纯度: ≥90% (HPLC)
• 相关基因信息: human ... PGGT1B(5229)
• 外观: colorless film
• 外观: lyophilized
• 熔点: 99.5-100 °C
• 溶解度: DMSO: >20 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
GGTI 298 is a cell-permeable, prodrug form of the geranylgeranyltransferase I (GGTase I) inhibitor GGTI-297. It inhibits the processing of Rap 1A without effecting the processing of H-Ras.

详细说明 (简体中文)

Biochem/physiol Actions
GGTI 298 is a cell-permeable, prodrug form of the geranylgeranyltransferase I (GGTase I) inhibitor GGTI-297. It inhibits the processing of Rap 1A without effecting the processing of H-Ras.