Wogonin hydrate

• 产品号: W0769
• CAS号: 632-85-9(anhydrous)
• 分子式: C16H14O6
• 分子量: 302.27876
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Wogonin hydrate
• IUPAC标准名: 5,7-dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one hydrate
• IUPAC传统名: wogonin hydrate
• 别名: 5,7-Dihydroxy-8-methoxyflavone

产品登记号

• MDL号: MFCD12828871
• CAS号: 632-85-9(anhydrous)

产品性质

• Empirical Formula (Hill Notation): C16H12O5 · xH2O
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: DMSO: ≥20 mg/mL
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: LK8331000
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Wogonin is an anti-inflammatory agent and COX-2 inhibitor, which inhibits the induction of both iNOS and COX-2. Wogonin inhibits COX-2 (IC50 = 46 μM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. Specifically, Wogonin inhibits NF-kappaB-mediated iNOS induction.

详细说明 (简体中文)

Biochem/physiol Actions
Wogonin is an anti-inflammatory agent and COX-2 inhibitor, which inhibits the induction of both iNOS and COX-2. Wogonin inhibits COX-2 (IC50 = 46 μM) without affecting COX-1. Wogonin inhibits iNOS induction and thus inhibts activation-induced C6 glial cell death. Specifically, Wogonin inhibits NF-kappaB-mediated iNOS induction.