Toloxatone

• 产品号: T3452
• CAS号: 29218-27-7
• 分子式: C11H13NO3
• 分子量: 207.22582
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: Toloxatone
• IUPAC标准名: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one
• IUPAC传统名: toloxatone
• 别名: Humoryl; 5-(hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone

产品登记号

• MDL号: MFCD00865391
• EC号: 249-522-2
• CAS号: 29218-27-7

产品性质

• Empirical Formula (Hill Notation): C11H13NO3
• 纯度: ≥98% (HPLC)
• 外观: solid
• 溶解度: DMSO: >10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• 危险公开号: 22
• RTECS编号: RQ2867500
• 保存条件: desiccated
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. Toloxatone belongs to the aryloxazolidinones, a relatively new class of reversible monoamine oxidase A inhibitors (MAOI). Studies show that derivatives such as 3-aryloxazolidin-2-one (oxazolidinones), which are regularly used to treat gram positive infections, represent a new class of reversible as well as irreversible inhibitors for MAO-A and MAO-B enzymes that are able to inhibit protein synthesis and also used for neurodegenerative-type pathologies.

详细说明 (简体中文)

Biochem/physiol Actions
Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. Toloxatone belongs to the aryloxazolidinones, a relatively new class of reversible monoamine oxidase A inhibitors (MAOI). Studies show that derivatives such as 3-aryloxazolidin-2-one (oxazolidinones), which are regularly used to treat gram positive infections, represent a new class of reversible as well as irreversible inhibitors for MAO-A and MAO-B enzymes that are able to inhibit protein synthesis and also used for neurodegenerative-type pathologies.