Ibandronate 钠 一水合物

• 产品号: I5784
• CAS号: 138844-81-2
• 分子式: C9H22NNaO7P2
• 分子量: 341.210772
• 纯 度: ≥97% (NMR)
• 保 存: protect from light

产品别名

• 标题: Ibandronate sodium salt
• IUPAC标准名: sodium hydrogen {1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl}phosphonate
• IUPAC传统名: sodium hydrogen 1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropylphosphonate
• 别名: Boniva; (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid 钠 一水合物; (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium; Bondronat

产品登记号

• MDL号: MFCD07197214
• CAS号: 138844-81-2

产品性质

• Empirical Formula (Hill Notation): C9H22NNaO7P2
• 纯度: ≥97% (NMR)
• 外观: white solid
• 溶解度: H2O: >10 mg/mL
• 保存条件: protect from light
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium is also a bone resorption inhibitor. It has been investigated for in vitro anti-tumor effects, such as apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, and inhibition of angiogenesis and for its in vivo role in various cancers including breast and prostate cancers.

详细说明 (简体中文)

Biochem/physiol Actions
Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium is also a bone resorption inhibitor. It has been investigated for in vitro anti-tumor effects, such as apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, and inhibition of angiogenesis and for its in vivo role in various cancers including breast and prostate cancers.